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One significant effect of cMyc overexpression is the upregulation of GLS1, an enzyme responsible for converting glutamine into glutamate
Bioinformatics analysis of ferroptosis in spinal cord injury
However, the increase in mGluRs-dependent signaling in the mouse model of FXS was not confirmed in human-based models, and clinical trials with mGluR inhibitors failed to produce a therapeutic effect in FXS patients [331]
