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In particular, increasing number of studies show that aberrant expression and activity of GRKs in the cardiovascular system and kidney inhibit or stimulate GPCRs (e.g., dopamine receptors, Ang II receptors, and - and -adrenergic receptors), resulting in hypertension

The VPA-exposed group exhibited activated microglia characterized by hypertrophic morphology with significantly elevated Iba1 fluorescence intensity compared to the control group (P 0.05)

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