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Baker JL, Mark Welch JL, Kauffman KM, McLean JS, He X

41 Slc3a2-dependent BCAA metabolism also has a key role in the physiological activities of Foxp3 + Treg cells, and either BCAA deprivation or SLC3A2 mutation can induce impaired activation of the mTORC1 pathway in Treg cells and inhibit the immunosuppressive function of Treg cells

Vilcinskas A
10.1073/pnas.1110444108 Proc
