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Yes, they can

Chen L, Na R, McLane KD, Thompson CS, Gao J, Wang X et al (2021) Overexpression of ferroptosis defense enzyme Gpx4 retards motor neuron disease of SOD1G93A mice

It is also more common in older adults, as the bodys ability to absorb vitamin B12 from food decreases with age

For an AOP, one often uses ozone combined with hydrogen peroxide (H 2 O 2 ), or ozone and UV-light, or hydrogen peroxide and UV-light
