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et al., 2022) (Figure 1A), recent studies highlight complementary in situ strategies

This effector domain has a typical winged helix-turn-helix fold of the OmpR/PhoB subfamily of RRs [323], in which the helix-turn-helix motif is formed by helices 7 and 8, and the wing motif is formed by the C-terminal -hairpin turn

Two studies using recombinant expression of the histidine-rich domain of SELENOP (SelP-H) in neuroblastoma cells revealed the molecular mechanism by which SELENOP intervenes in A aggregation and neurotoxicity through metal ion homeostasis

Further generation of glycine from serine is controlled by a bidirectional conversion catalyzed by serine hydroxymethyltransferases (SHMTs), SHMT1 in the cytosol and SHMT2 in mitochondria
