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Sleep 38 , 19451953 (2015)

10.1039/c9sc01070j 72 XiangH.YouC.LiuW.WangD.ChenY.DongC

For instance, elevated CHAC1 mRNA levels are associated with increased recurrence risk in these cancers, underscoring its clinical relevance ( Pan-cancer analyses reveal that CHAC1 expression is highly variable, being upregulated in many cancers (e.g., breast, ovarian, lung, bladder carcinomas) and downregulated in others (e.g., certain head/neck, kidney, and brain cancers) (Zhang, T

Overall, phosphorylation of NRF2, as a dynamic and reversible protein modification, is important for the regulation of signaling and biological processes inside and outside the cell (Table 1)