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A retrospective human study examined 16 patients receiving intra-articular BPC-157 injections for knee pain

Achermann JC, Hindmarsh PC, Brook CG

S., & Kim, N

In the hypothalamus, early-life stress resulted in a marked atrophy of astrocytes, aberrant purinergic signaling and limited supply of L-lactate, leading to a pathological activity of orexin neurons driving aberrant behaviors 277
