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doi: 10.1016/S1043-4666(03)00101-7
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This ATF4-mediated induction is often triggered by the GCN2-eIF2 pathway when uncharged tRNAs accumulate (a sign of amino acid deprivation) [23]
In another cruel twist, we have found that strains that have a functional IRC7 gene do not make the enzyme in wort because the gene is turned off in the presence of high nitrogen levels common to wort
