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The importance of GST A3-3 is shown by inhibiting the enzyme with drugs or by RNA interference of GST A3-3 biosynthesis, treatments which both suppress the hormone production in two steroidogenic human cell lines (Raffalli-Mathieu et al., 2008)

Spond, J

The depressive-like behavior induced by social defeat stress in adolescent mice was also ameliorated by clemastine treatment (Shimizu et al., 2020)

Parenteral Gln supplementation combined with enteral nutrition increased plasma and tissue Gln concentrations by upregulating the expression of heat shock protein 90 (Hsp90) and attenuated apoptosis in the lymphoid organ spleen and circulating lymphocytes, ultimately enhancing immune function and improving survival in severely burned rats (36)