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This is likely to be due to an increased central sympathetic output, since clonidine reduced resting norepinephrine overflow, MBP, HR, and TPR through a central action in SHR but not WKY (9)
For example, lutein and lycopene protect the retina from oxidative damage by reducing the production of ROS inside and outside the cells [447]

[Google Scholar] 165.Mohamed Husien H., Peng W., Su H., Zhou R., Tao Y., Huang J., Liu M., Bo R., Li J

reduce pathological damage and oxidative stress in the liver of alcohol-exposed mice
