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GPx activity in plasma and saliva did not correlated with platelets in patients with CD, however, a positive correlation was noted in plasma of the control group

The respective loading plots revealed the resonances relevant for class separation, which were selected for area integration (AMIX 3.9.14, Bruker BioSpin, Rheinstetten, Germany), normalization, and variation assessment by univariate analysis

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Further, in vivo experiments on IL-6 transgenic mice with chronic inflammation revealed similar alterations in the cerebellum, characterized by increased microglial number and activation, pronounced neurodegenerative changes, and significant loss of PCs (Childs et al., 2021)