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Nodules, eosinophilia, rheumatism, dermatitis and swelling (NERDS), episodic angioedema with eosinophilia (Gleich syndrome), urticaria, eosinophilic cellulitis (Wells syndrome), and insect bite reactions demonstrate variable degrees of edema that are probably explained, at least in part, by this mechanism (see Chapter 36)

Hcy is however also used for the synthesis of glutathione (GSH) via cystathionine and cysteine, a metabolic route called the transsulfuration pathway (Hcy cystathionine cysteine GSH), which could potentially have been inhibited by MTAN expression and DZnep

10.1002/(SICI)1098-1136(20000101)29:1 3.0.CO;2-V 37

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