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Even though edavarone seems to be of value in neurological disorders, it has limited ability to cross the BBB
Mutants that have a low ascorbate content have significant reprogramming of gene expression, including genes involved in hormone synthesis and signalling, as well as photosynthesis and defence (Kiddle et al
[15] Synthetic thyroxine was first successfully produced by Charles Robert Harington and George Barger in 1926
Shimada et al., 2011
