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However, IL-28B induced superior CTL responses and significantly higher granzyme B mRNA levels, suggesting more robust activation of cytotoxic effector pathways ( GM-CSF Granulocyte-macrophage colony-stimulating factor (GM-CSF), also known as colony-stimulating factor 2 (CSF2), is a monomeric glycoprotein secreted by macrophages, T cells, mast cells, natural killer cells, endothelial cells, and fibroblasts that functions as a pleiotropic cytokine that drives differentiation of myeloid precursors into APCs, enhances DC maturation, and supports the generation of T H 1-biased immune responses

doi: 10.1038/nrn3875

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