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As for PDPN targeting, the relief of the inhibitory signal delivered through the CD47-SIRP- binding on macrophages could generate a pro-inflammatory TME favoring the anti-MB immune response, as indicated for other tumor types (287, 288)
[DOI] [PubMed] [Google Scholar] Kuo PC, Abe KY, Schroeder RA
The increased surface area of Au-NPs is believed to enhance their effectiveness 24
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