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Description
The final products of peroxisomal -oxidation can reach mitochondria after conjugation with carnitine trough carnitine octanoyltransferase (CrOT) (whose substrates are medium and long-chain fatty acyl-groups) or peroxisomal carnitine acetyltransferase (CrAT), which is more active toward short-chain acyl-CoAs [18, 66]
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This study also reported that increased serum L-carnitine levels were associated with significantly more atherosclerotic plaque in the 2,595 people who underwent elective cardiac screening, but only in those whose TMAO levels were also elevated
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