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D-Serine, synthesized by serine racemase in both astrocytes and neurons, serves as a co-agonist at NMDA-type glutamate receptors, playing a pivotal role in modulating synaptic plasticity and possibly influencing neuronal recovery processes, although its role in axonal regeneration remains to be fully defined [101]

2.2.2 Pancreas Pancreatic -cell dysfunction is prevalent in PCOS patients, which significantly contributes to their abnormal glucose tolerance and the long-term risk of developing type II diabetes mellitus (T2DM) (73, 74)

Ras proteins induce senescence by altering the intracellular levels of reactive oxygen species

Quantification of cytoplasmic localization To assess the cytoplasmic localization of fluorescence, we adapted protocols 42 to focus exclusively on intestinal cells