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NAC helps maintain this balance by supporting glutathione production

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Specifically, NOTCH2 restricts the differentiation of basal cells, while NOTCH3 can inhibit secretory differentiation (Carraro et al., 2020)

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In addition, astrocytic connexin channels, which regulate the transport of adenosine triphosphate (ATP), glutamine and glucose, exhibit altered expression patterns in disease states, shifting astrocytes toward either a neuroprotective or neurotoxic metabolic profile 76

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Acosta-Torres, L.A

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