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Conflict of interest The authors declare that they have no competing interests

Association of nocturnal hypoxemia with progression of CKD

It is thought that genetic, epigenetic, and environmental factors each play a role, but the exact nature of this relationship is still being explored

The 5xFAD transgenic mouse line has been genetically engineered to model features of AD through the expression of human amyloid precursor protein (APP) and presenilin-1 transgenes, which are associated with earlyonset AD [21]
