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The drug was particularly effective in patients with aggressive clinical and molecular profiles, such as WHO grade IV gliomas, IDH-wildtype tumors, and 1p/19q non-codeleted gliomas

SURPASS-CVOT (N=13,165) noninferior on 3-point MACE (HR 0.92), significant on 4-point MACE (0.88) and all-cause death (0.84): Heerspink SURPASS-4 kidney post-hoc

[DOI] [PMC free article] [PubMed] [Google Scholar] Phillips C
