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In contrast, astrocytes exhibit lower expression of pyruvate dehydrogenase (Laughton et al., 2007), which limits oxidative phosphorylation (Itoh et al., 2003) and reduces pyruvate utilization efficiency in the TCA cycle (Rahman et al., 2020)

But right now, the drug is still being tested

Interestingly, individuals with food allergies, especially those allergic to lipid transfer proteins would likely be at risk of developing an allergic reaction from the consumption of L

6-Phosphogluconolactonase: PGLS The product of the glucose-6-phosphate dehydrogenase reaction, 6-phosphogluconolactone, is converted to 6-phosphogluconate by the enzyme, 6-phosphogluconolactonase which is encoded by the PGLS gene
