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Description
MTHFR polymorphisms can affect folate availability for these pathways
Cleavage of GCLC occurs at Asp 499 within the sequence AVVD 499 G, which is located upstream of Cys 553 thought to be important for disulfide bond formation with GCLM [35,45]
These ocular delivery challenges impede the translation of ferroptosis-targeted therapies, emphasizing the urgency for novel targeted and sustained drug delivery systems
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