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doi: 10.1038/nature08192 11 StefanssonHOphoffRASteinbergSAndreassenOACichonSRujescuDet al

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Supporting evidence for the prefrontal hypodopaminergia came from PET (positron emission tomography) studies showing reduced cerebral blood flow in frontal cortex, which was directly correlated with low cerebrospinal fluid (CSF) DA metabolite levels in schizophrenia patients

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