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The -(4-bromo-phenyl)-2-(4-(2-methoxyphenyl)-5-phenyl-4-1,2,4-triazol-3-ylthio)acetamide scaffold from the series of newly reported derivatives demonstrated 3500-fold stronger tyrosinase inhibition efficacy with IC 50 value 0.0048 0.0016 M towards mushroom tyrosinase enzyme as compared to standard reference compound kojic acid having IC 50 value 16.8320 1.1600 M
The ideal candidate is someone who has a meaningful fat-loss goal, defined as 20 lbs or more to reduce, who is also concerned about how skin quality and connective tissue integrity will hold up through that process

2006 Aug;13(3):171-81
