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Cellular studies of the inhibitory capacity of CLR01 in two different models suggested that the molecular tweezer could reduce the toxicity of endogenously expressed and aggregated -Syn and decrease the administrations toxic effect of exogenous -Syn oligomers, increasing the cell viability [306]
Cell 181 , 10161035.e9 (2020)
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Biochem Pharmacol 36:747755 Schmitz Y, Lee CJ, Schmauss C, Gonon F, Sulzer D (2001) Amphetamine distorts stimulation-dependent dopamine overflow: effects on D2 auto receptors, transporters, and synaptic vesicle stores
