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Description
PMCID: PMC7533855
Depending on the cellular redox milieu and cell type, Fos and Jun can dimerize or interact with other transcription factors such as ATF, C/EBP and Maf leading to activation or inhibition of gene transcription of antioxidant and immunoactive proteins (169, 360)
After rinsing with PBS, the sections were incubated with Cy3-conjugated goat-anti-mouse (115-165-003, 1:200, Jackson Immuno Research) for 1 hour at room temperature in the dark
Clinical studies have evaluated doses ranging from 1 mg to 12 mg weekly with gradual dose escalation commonly used to improve tolerability
