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doi: 10.1111/cen.2014.81.issue-1 13 ShishkoPIDrevalAVAbugovaIAZajarnyIUGoncharovVC
Role in disease [edit source] Mutations in the first SOD enzyme (SOD1) can cause familial amyotrophic lateral sclerosis (ALS, a form of motor neuron disease)
GSTs may also be viable drug targets in disease states unrelated to cancer
Furthermore, epigenetic age acceleration (EAA), an epigenetic biomarker of aging, has been linked to indoor air pollution from coal combustion and associated pulmonary arterial hypertension, particularly 5-methylcytosine, which correlates with the mortality biomarker Grim Age EAA [158]
