ipamorelin causing increase in estradiol (2mg): The Growth Hormone Peptide For Recovery, Performance, And Longevity Will Ipamorelin Increase Testosterone?
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doi: 10.1016/S0006-8993(96)00910-9
Although serious adverse effects are rare, the incidence of minor adverse events may be considerable

C.EtheveS.ChenalE.et al (2017)

Commodity pages often place sermorelin in the same risk category as recombinant human growth hormone (rhGH)