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However, all the aforementioned drugs or ingredients have varying degrees of side effects, which can not only impact therapeutic efficacy but also lead to adverse reactions within the human body

In a mouse model with subclinical inflammation, it was shown that extracellular vesicles released by ATP-stimulated microglia cause a strong inflammatory reaction in glial cells in vitro and can propagate an inflammatory response among microglia (Verderio et al., 2012)

Aging Cell 13 , 408418 (2014)

There were no significant differences in the proportion of patients from each study group reporting symptoms in a daily diary (Supplemental Table S-2b)