l carnitine fumarate wiki MetaboliteoftheMonth: #Succinate Succinate is a metabolic multitasker—the only tricarboxylic acid (TCA) cycle metabolite that is also part of the electron transport chain. As a substrate for succinate dehydrogenase (Complex II), it links Carnitine - wikidoc
Description
It has been attributed to left atrial enlargement and dilation in mitral annulus as the primary mechanism for mitral leaflet malcoaptation (6)

10.1016/j.neulet.2014.02.023 Neurosci
This was also confirmed by the high expression of CPT1 mRNA in the liver and muscle of the L-carnitine-fed zebrafish, and the comparable mRNA expressions of ACO in both tissues between the groups

To maximize its benefits, pair L-Carnitine supplementation with lifestyle adjustments such as maintaining a balanced diet, engaging in regular exercise, and managing your weight
