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It is essential for several physiological activities, such as antioxidant defence, detoxification, immune system function, and skin lightening

[DOI] [PMC free article] [PubMed] [Google Scholar] 50.Nhr M.K., Egerod K.L., Christiansen S.H., Gille A., Offermanns S., Schwartz T.W., Mller M

Proliferation of murine c-kitpos cardiac stem cells stimulated with IGF-1 is associated with Akt-1 mediated phosphorylation and nuclear export of FoxO3a and its effect on downstream cell cycle regulators
