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It is known that tumor-associated macrophages (TAMs) in the tumor microenvironment (TME) are actually M2-like polarized macrophages, which can suppress anti-tumor immunity (54)

J Thorac Oncol 6(8):1304-12, 2011

LDH activity was determined spectrophotometrically at 340 nm by following the rate of NAD + reduction in the presence of l-lactate

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