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Remarkably, the charge distribution and shape of TrxR1 in this site is different with respect to TGR 33 due to the presence of charged and bulky residues, i.e., E337, D338, E341, E368 and K389 in human TrxR1 in place of A436, G437, Q440, S467 and D488 in TGR
10.1016/j.bcp.2017.09.010 110 TakayanagiH
