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Description
In mice, intranasal administration for five consecutive days increased the phosphorylated GSK-3 to total GSK-3 ratio in the hippocampus in a dose-dependent manner, with significant effects at 10 and 100 milligrams per milliliter
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Moreover, global deletion of IGF-1 gene expression in mice does not result in glucose intolerance
This review discussed various recent approaches to modulate -Syn expression and aggregation, including gene therapy and cellular transplantation
