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10.3389/fphar.2019.00352 5 BelardoC.AlessioN.PaganoM.De DominicisE.InfantinoR.PerroneM.et al (2022)

ERK1/2 Additionally, the extracellular signal-regulated kinase (ERK1/2) pathway is also activated

Cancer cells with high glycolytic activity (e.g., tumors with pronounced Warburg effect) have elevated NADH levels, providing sufficient electron donors for FSP1 and enhancing its anti-ferroptotic capacity
