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Specifically, the data implied that colonic epithelial inflammation was the result of a metabolic abnormality, which resulted in impaired redox homeostasis leading to excess production of hydrogen peroxide by colonic epithelial cells

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Following implementation of universal premarital screening and counseling in the 1970s, the number of births of children with Thalassemia Major fell from over 50 per year to nearly zero within two decades, without coercive measures, highlighting the power of informed reproductive choice

The human metabolome database [242] contains nearly 221,000 entries of metabolites, which are categorized by disease, age, gender, and source (serum, urine, feces, cerebrospinal fluid, sweat) and enriched with structural data