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The substance itself is not stored in the body, and the rate of its synthesis is proportional to the rate of its release into the bloodstream. MELATONIN SYNTHESIS In the body, melatonin synthesis occurs thanks to the action of its precursor, which is tryptophan taken from the blood

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The compound's high membrane permeability and metabolic stability make it suitable for both acute and chronic study designs, but researchers should be aware that its effects on NAD+ and methylation metabolism may require time to fully manifest