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CAR T cells of LTR show high immunometabolic polyfunctionality post-infusion supported by the bone marrow (BM) microenvironment To study the relationship between immunometabolism and CAR T cell anti-tumor activity in patients, we examined day 28 post-infusion BM samples (Fig
In addition to these mechanisms, oxidative stress activates multiple MAPK pathways, including p38 MAPK, JNK, and ERK1/2

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