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This enzyme is encoded by the asparaginase (ASPG) gene

FIGURE 3 Inorganic Se (selenite and selenate) may cross the BBB and BCB using inorganic anion transporters, which are present in the barriers ( + -sulfate/carboxylate co-transporter family (Hu et al., 2020)] may be responsible for carrying selenate across the barrier since it is isomorphic to sulfate

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An even more challenging task will be to elucidate the functional impact of such changes, both in terms of their quantitative influence on the biological activity of the affected protein, as well as their fractional control over the integrated network of subcellular and cellular regulation