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Description
Methylcobalamin should be taken in the dose and duration advised by your doctor
In this context, cells reroute glutamine into the reductive carboxylation pathway: NADP + -dependent isocitrate dehydrogenase runs in reverse to convert -ketoglutarate (from glutamine) into citrate, which is cleaved to acetyl-CoA for fatty acid synthesis 98
For both high and low metal concentrations it is interesting to measure E GSSG/2GSH after metal treatment in order to determine cell viability in future studies
Therefore, it is critical to understand the cellular processes that contribute to drug-induced plasticity
