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Anti-inflammatory Effect of Sulforaphane through the Suppression of COX-2 Expression Classical anti-inflammatory compounds such as aspirin, indomethacin, ibuprofen, and diclofenac as well as the newer generation of selective COX-2 inhibitors (e.g., celecoxib) target the enzymatic activity of COX-2, while others, including steroidal anti-inflammatory agents, suppress the induced expression of COX-2

Amino acids are sequentially added to resin, followed by cleavage, controlled oxidation to form the disulfide bond, and purification

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doi:10.1111/j.1478-3231.2012.02857.x Hossain KFB, Akter M, Rahman MM, et al