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and astrocytes transition from neurosupportive roles of sustaining neuronal energetics via lactate shuttling to neurotoxic contributors through chronic lipid droplet accumulation that exacerbates neuroinflammation

MC3R activation has been associated with regulation of adipogenesis, inflammatory mediator release, and natriuretic signaling in animal model research (Butler et al., Endocrinology, 2000)

Griffiths HR, Lunec J
[DOI] [PubMed] [Google Scholar] 162.Pang SM, Le S, Kwiatkowski AV, Yan J