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In addition, hTrx1 can bind to Dectin-1 and/or Dectin-2 on antigen presenting cells to secret IL-1 and IL-23, which influence Th2/Th17-polarizing milieu during the allergic sensitization in the skin (82)

[7] [25] Prostaglandin E2 (PGE2) is an essential activator of the canonical Wnt signaling pathway

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92 At modest concentrations, NO exerts a protumorigenic response that may benefit tumor growth and survival
