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doi: 10.1016/j.jconrel.2025.113604 45 ChenY.ZhangC.HuangY.MaY.SongQ.ChenH.et al

But here are some general guidelines: Severe deficiencies: Daily shots for 1 week, then weekly shots until levels normalize Moderate deficiencies: Weekly shots until the deficiency is corrected Maintenance dosing : Monthly shots to keep B12 levels optimal Its definitely possible to take B12 shots too often

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