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Description
Deletion of the NAC region from S results in a high resemblance of beta-synuclein (S), a less neurotoxic synuclein, with some claims that it may also reduce and protect against S neurotoxicity [56]

Other possible targets of EGCG could be NMNAT2 to promote the synthesis of NAD from nicotinamide [73], tau clearance [74], and inhibition of A oligomerization [75]
The latter is consistent with the well-known beneficial effect of MSCs on articular chondrocytes [40]

[PubMed: 16154439] 67