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Funding This research was supported by the INSERM, Universit Cte dAzur, the Fondation ARC pour la Recherche contre le Cancer (Equipe Labellise 20222025), the Canceropole PACA, a grant from PLBio (R19003AP-20192023), ITMO cancer 20192023 and the Association Laurette Fugain (ALF)

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Full assembly equilibrium was attained at 12 h and 60 h, suggesting that PSMA binding stabilizes intermediate conformations to bypass high-energy nucleation barriers