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Thus, while IN chelation is promising for directly targeting the brain and CNS, it still requires careful consideration of formulation strategies (e.g., nanoparticle targeting or controlled-release systems) to improve site specificity, especially for drugs with a narrow therapeutic window
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Adequacy of analgesia is assessed, and modifications to the pain management plan are made
[DOI] [PubMed] [Google Scholar] 121.Jones P.A., Takai D
