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Description
Many men on testosterone replacement therapy (TRT) initially fear high estradiol levels since they fear it causes water retention and gynecomastia
The initial outcome can be observed within 30 days
If your T is already in the normal-to-high range (600+ ng/dL), enclomiphene likely won't move the needle dramatically for muscle growththough you might still benefit from improved energy and recovery
Additionally, significant associations were observed between single nucleotide variants in the NNMT gene and energy metabolism, obesity, T2D, hyperlipidemia, and hypertension (Zhu et al., 2016
