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At higher doses, some concern exists about pro-inflammatory effects: LL-37 can activate NF-kB pathways, potentially worsening certain inflammatory conditions

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Once inside the brain, the enzyme Aromatic L-amino acid decarboxylase (AADC) converts Levodopa into active dopamine, which is then stored and released to temporarily restore dopaminergic signaling and improve motor function

above 25C for more than 24 hours renders the vial unusable