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J Neurochem 97:687696 Tulpule K, Dringen R (2011) Formaldehyde stimulates Mrp1-mediated glutathione deprivation of cultured astrocytes

Subacute tests revealed no significant differences in histomorphology, blood biochemistry, or blood counts

However, despite promising preclinical results, the clinical translation of SIN is limited by its poor pharmacokinetic profile, including low oral bioavailability and rapid systemic clearance

Cortex 16, 12891295
